Is bipolar genetic? Can I get bipolar?
Genetics can reveal the origins of some mental disorders, but a new study from researchers at the University of Toronto suggests it could also help explain some of the genetic variations seen in the disorder.
The study, published in the Journal of Medical Genetics, is based on a genetic study of more than 40,000 people who were found to have bipolar disorder.
Researchers looked at the genomes of people with the disorder, who were also tested for their genetic makeup.
This is the first study to look at a genetic component of bipolar disorder and its genetics.
The researchers were interested in a genetic link between the disorder and genes that may be responsible for some mental health disorders, like bipolar disorder, which have been linked to a genetic predisposition for the disorder in people with bipolar disorder but not in those without it.
The team analyzed the genomes from more than 20,000 individuals with bipolar and in-person interviews with people with and without the disorder revealed that nearly all people with diagnosed bipolar disorder have a specific genetic variation, with some having as many as six different variants.
These variants may affect the way genes regulate dopamine levels, mood and behaviour, and can affect neurotransmitters in the brain.
The genetic variation in people who have bipolar is similar to other mental health conditions, including schizophrenia, bipolar depression, post-traumatic stress disorder and schizophrenia.
There are a number of studies that have linked genes to mental health issues, including autism, ADHD, attention deficit hyperactivity disorder, and schizophrenia and depression.
However, many studies have been based on the assumption that people with mental health problems are genetically predisposed to develop mental health diagnoses, and that a genetic cause for the mental health condition is unknown.
The research team from the University at Buffalo, University of Montreal, and the University in Toronto looked at a large number of people in Canada who were randomly assigned to have a test of their genes or their environmental exposures, and compared these with people who had never had the disorder or who did not have any mental health history.
The findings were pretty interesting, the team said in a press release.
People with bipolar are more likely to have different genetic variants than people without bipolar, and their genetic variations are associated with their risk for mental disorders.
People who had a genetic variant for bipolar disorder were more likely than others to have schizophrenia and a bipolar disorder diagnosis, and people with a genetic variation for bipolar depression were more than those without.
It’s possible that having this genetic variation may contribute to some of these mental health difficulties, the researchers said.
This finding has implications for how to treat people with this disorder, the study said.
“This study suggests that genetic variants for bipolar affect how we think about and treat mental health symptoms, so we need to learn more about how those genetic variants interact with each other to determine the best approach to treating this disorder,” said study co-author Andrew Mazzocchi, a professor in the Department of Psychiatry at the university.
“We have shown that there are a variety of genetic variants associated with bipolar that are important for its development, but we don’t know how they interact with one another to cause mental health disorder.”
The researchers said they plan to continue to follow people with psychiatric disorders in the future and look for new genetic variants to further understand the genetic component.
You can read more about the study in the press release, but here’s a video from the researchers explaining their findings.