Dogs tested for genetic test link to autism spectrum disorder
Dog genetic testing has been linked to autism, a major concern for many parents who worry their furry friends might be at risk.
A new study suggests that dogs that have been tested as part of a genetic test could be at increased risk of the condition.
In addition to increasing the number of dogs with the condition, the study also found that dogs with a genetic condition were more likely to have an affected family member or friend.
The researchers analyzed DNA samples from 1,065 dogs from five different breeds, including Staffordshire bull terriers, American bulldogs, Labrador retrievers, Great Danes, and American Staffordshire terriers.
The dogs were tested for the presence of a mutation in a gene called GAPDH, which causes autism.
The study found that the dog with the mutation had a 50 percent increased risk for autism, compared to a control group.
This increase was not statistically significant, the researchers wrote in the study, but it did seem to be associated with autism.
“Although these results are in line with previous studies, this is the first case of a dog having a GAPDHA mutation associated with an ASD phenotype,” the study’s lead author, Dr. David Pemberton, told ABC News.
“It does not mean that this mutation will result in autism.”
The genetic mutation occurs in dogs as early as one week of age, according to the study.
The mutation causes the dog to have the “non-reactive” phenotype of the affected dog.
It is not clear what causes this non-reactivity.
It could be due to a genetic predisposition or it could be a genetic response to a toxic environment.
Dr. Pemberland told ABC that this study is important because the increased risk may be due in part to the dogs being exposed to the toxin in the womb.
A fetus is not able to produce its own GAPDHR gene, and therefore the mutated dog would not have a normal genetic response.
Dr Pemberdale said the mutation has been shown in dogs with ASD, but there have been no studies of the risk to the general population.
“What this study shows is that there are dogs who are at a higher risk for developing autism,” he said.
“So this is really important because we really don’t know if there is a causal relationship between the mutation and autism.”
A genetic association of autism and GAPDHTThe researchers say that because the mutation does not affect the animals’ normal function, it does not necessarily indicate a connection between the genetic mutation and the condition or the dog’s condition.
“The question is, are the dogs of these dogs that are more susceptible to developing autism, or are they more likely than others to develop autism?
I don’t think that’s an answer that is definitive,” Pemberlund said.
The team found that there was a significant increase in the number, type, and severity of the disorders in dogs that had the mutation, compared with dogs with controls.
The study also suggested that the genetic risk for ASD increased by up to 50 percent, compared the control group, which had been matched for the same risk factors.
“Our findings suggest that a genetic variant associated with a higher incidence of autism might be present in dogs of affected dogs,” the authors wrote.
“This suggests that a causal association between the GAPDHP mutation and ASD might exist, but that such a relationship is not yet fully established.”
The study was published in the Journal of Genetics in May.ABC News reached out to the company that provides the dogs with testing for GAPDHE, Dog Genetics, to find out more about the study and whether the company plans to change its genetic testing protocol.
Dog Genetics issued the following statement: “Dog Genetics is committed to the safety and well-being of our customers.
We conducted this study in the privacy of our dogs’ homes and the dogs were not given any kind of test.
“We have been working with our regulatory partners and regulators to ensure that we are abiding by the safety regulations. “
We look forward to further research in the coming months to confirm this finding.”ABC News’ Michael A. Marks contributed to this report.”
We have been working with our regulatory partners and regulators to ensure that we are abiding by the safety regulations.
We look forward to further research in the coming months to confirm this finding.”ABC News’ Michael A. Marks contributed to this report.