Which genes are related to obesity?
Genetics experts are calling for more research to determine whether genetic differences between African-American and white Americans are related and whether certain variations in genes linked to obesity could be used to develop obesity-fighting drugs.
In a study published Tuesday in the American Journal of Human Genetics, researchers analyzed data from the National Health and Nutrition Examination Survey (NHANES), a nationally representative sample of the nation’s adult population.
The researchers looked at more than 14,000 DNA samples from people born between 1954 and 1973.
They found that African-Americans who were born in the 1940s and 1950s had a 1.3-point higher risk of obesity compared to whites born in those years.
Researchers also found that genetic differences among African- Americans were correlated with greater rates of obesity in their children.
The authors say their results support the hypothesis that African Americans are genetically predisposed to obesity, which has been linked to metabolic disease and other health problems.
The results are consistent with previous research linking genetic differences to body mass index (BMI) in both African- and white-American individuals, said Dr. David R. Katz, the study’s senior author and a professor of medicine and public health at Johns Hopkins University.
The study also indicates that there are more genes that are associated with obesity than have been previously linked, Katz said.
For example, there are about 500 genes in the genome that are linked to weight.
The more genes there are, the greater the risk of having obesity-related diseases.
This is the first time that a large population has been identified, Katz told NBC News.
He and his colleagues say their analysis has some limitations, but that the research could lead to better interventions to combat obesity.
The researchers used data from more than 7 million individuals, representing more than half the U.S. population, from the NHANES, which began in 1958.
The data were analyzed using the most recent version of the National Center for Health Statistics’ BMI system, which takes into account the weight of the person at the time of their birth.
The research team used data on the genes in people’s genomes to estimate the genetic risk of different obesity genes.
They used the most widely used genetic tests, including the HLA-DQ2 gene, which is associated with blood sugar control.
They also used information from genetic information from a sample of African Americans who had their weight measured and compared it with the genetic information for white Americans.
In addition, the researchers used a genetic algorithm to compare people’s BMI and genetic data to determine the genetic contribution to obesity.
This is the method used to identify genes that may be involved in a disease.
The analysis of the genetic data showed that the genetic differences were significant in nearly half of the individuals analyzed, Katz and his coauthors wrote in the study.
They also said their findings “confirm the possibility that obesity is not a genetic disorder and that the causal relationship between obesity and genetics is complex.”
The study was funded by the National Institutes of Health, and it was written by Katz and other researchers from the Johns Hopkins Medical Institutions and Harvard Medical School.
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